P2RY13
| Purinski receptor P2Y, G-protein spregnuti, 13 | |||||
|---|---|---|---|---|---|
| Identifikatori | |||||
| Simboli | P2RY13; GPCR1; FKSG77; GPR86; GPR94; P2Y13; SP174 | ||||
| Vanjski ID | OMIM: 606380 MGI: 1921441 HomoloGene: 12543 IUPHAR: P2Y13 GeneCards: P2RY13 Gene | ||||
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| Pregled RNK izražavanja | |||||
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| podaci | |||||
| Ortolozi | |||||
| Vrsta | Čovek | Miš | |||
| Entrez | 53829 | 74191 | |||
| Ensembl | ENSG00000181631 | ENSMUSG00000036362 | |||
| UniProt | Q9BPV8 | Q0VF10 | |||
| RefSeq (mRNA) | NM_023914 | NM_028808 | |||
| RefSeq (protein) | NP_076403 | NP_083084 | |||
| Lokacija (UCSC) |
Chr 3: 152.53 - 152.53 Mb |
Chr 3: 59.3 - 59.3 Mb | |||
| PubMed pretraga | [1] | [2] | |||
P2Y purinoceptor 13 je protein koji je kod ljudi kodiran P2RY13 genom.[1][2][3]
Proizvod ovog gena, P2Y13, je član familije G-protein spregnutih receptora. Ova familija ima nekoliko tipova receptora sa različitom farmakološkom selektivnosti za razne adenozinske i uridinske nukleotide. Oni se preklapaju u nekim slučajevima. Endogeni ligand ovog receptora je ADP. Dve transkriptne varijante koje kodiraju isti protein su poznate.[3]
Vidi još
[уреди | уреди извор]Literatura
[уреди | уреди извор]- ^ Wittenberger T, Schaller HC, Hellebrand S (2001). „An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors”. J Mol Biol. 307 (3): 799—813. PMID 11273702. doi:10.1006/jmbi.2001.4520.
- ^ Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (2001). „Discovery and mapping of ten novel G protein-coupled receptor genes”. Gene. 275 (1): 83—91. PMID 11574155. doi:10.1016/S0378-1119(01)00651-5.
- ^ а б „Entrez Gene: P2RY13 purinergic receptor P2Y, G-protein coupled, 13”.
Dodatna literatura
[уреди | уреди извор]- Communi D; Gonzalez NS; Detheux M; et al. (2001). „Identification of a novel human ADP receptor coupled to G(i).”. J. Biol. Chem. 276 (44): 41479—85. PMID 11546776. doi:10.1074/jbc.M105912200.
- Zhang FL; Luo L; Gustafson E; et al. (2002). „P2Y(13): identification and characterization of a novel Galphai-coupled ADP receptor from human and mouse.”. J. Pharmacol. Exp. Ther. 301 (2): 705—13. PMID 11961076. doi:10.1124/jpet.301.2.705.
- Takeda S; Kadowaki S; Haga T; et al. (2002). „Identification of G protein-coupled receptor genes from the human genome sequence.”. FEBS Lett. 520 (1–3): 97—101. PMID 12044878. doi:10.1016/S0014-5793(02)02775-8.
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899—903. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899.
Spoljašnje veze
[уреди | уреди извор]- „P2Y Receptors: P2Y13”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Архивирано из оригинала 03. 03. 2016. г.