Pantoprazol
(IUPAC ) ime
6-(difluorometoksi)-2- {[(3,4-dimetoksipiridin-2-il)metan]sulfinil1H-1,3-benzodiazol
Klinički podaci
Robne marke
Astropan, Pantoloc, Pantor, Pantozol
AHFS/Drugs.com
Monografija
Identifikatori
CAS broj
102625-70-7
ATC kod
A02 BC02
PubChem [ 1] [ 2] 4679
DrugBank
DB00213
ChemSpider [ 3] 4517
KEGG [ 4] C11806 Y
ChEMBL [ 5] CHEMBL7915 Y
Hemijski podaci
Formula
C 16 H 15 F 2 N 3 O 4 S
Mol. masa
383.37
SMILES
eMolekuli PubHem
InChI InChI=1S/C16H15F2N3O4S/c1-23-13-5-6-19-12(14(13)24-2)8-26(22)16-20-10-4-3-9(25-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21) Y
Farmakokinetički podaci
Poluvreme eliminacije
1 sat
Izlučivanje
71% urinom
Farmakoinformacioni podaci
Trudnoća
?
Pravni status
Način primene
Intravenozno; Oralno
Pantoprazol je inhibitor protonske pumpe koji se koristi za kratkotrajne tretmane erozije i ulceracije jednjaka uzrokovane gastroezofagealnom refluksnom bolešću [ 6] [ 7]
↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.” . Drug Discov Today 15 (23-24): 1052-7. DOI :10.1016/j.drudis.2010.10.003 . PMID 20970519 . edit ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4 : 217-241. DOI :10.1016/S1574-1400(08)00012-1 . ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining” . J Cheminform 2 (1): 3. DOI :10.1186/1758-2946-2-3 . PMID 20331846 . edit ↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG” . Yeast 17 (1): 48–55. DOI :10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H . ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI :10.1093/nar/gkr777 . PMID 21948594 . edit ↑ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035-41. PMID 21059682 . ↑ Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic Acids Res 36 (Database issue): D901-6. PMID 18048412 .
