Bentazepam
| obere ụdị nke | chemical compound  |
|---|---|
| usoro kemịkalụ | C₁₇H₁₆N₂OS |
| canonical SMILES | C1=CC=C(C=C1)C2=NCC(=O)NC3=C2C4=C(S3)CCCC4 |
| subject has role | hypnotics and sedatives |
Me mmadụ
Ọ nwere ihe na-eme ka nchegbu kwụsị, ihe na-egbochi nkụchi, ihe na'ime ka ọ dị jụụ na ekpere chi oboro ndị na eme ka ndị mmadụ ihe na-ehi ụra. A na-enweta ọnụ ọgụgụ kachasị elu nke plasma n'ihe dị ka awa 2.5 mgbe a nwesịrị ọgwụgwọ ọnụ.[1] Ọkara ndụ mwepụ ahụ dị n'etiti ihe dịka awa 2-4.[2][3] Bentazepam dị irè dị ka ihe na-egbochi nchegbu.
Nnukwu benzodiazepine na bentazepam nwere ike ịkpata coma na nsogbu iku ume.[4] Mmetụta ọjọọ gụnyere ọnụ kpọrọ nkụ, ụra, asthenia, dyspepsia, afọ mgbu, agbọ onunu[5] na ọgwụ na-akpata lymphocytic colitis ejikọtara ya na bentazepam.[6][7] A na-ejikọkwa mmerụ ahụ imeju siri ike na ịba ọcha n'anya na bentazepam.[8][9][10] Ọ bụ ezie na a na-ewere ọdịda imeju site na bentazepam dị ka ihe a na-adịghị ahụkebe, a tụwo aro nlekota ọrụ imeju maka ndị ọrịa niile na-aṅụ bentazepam.[11]
Hụkwa
[dezie | dezie ebe o si]- Ndepụta nke benzodiazepines
Ntụaka
[dezie | dezie ebe o si]- ↑ (November 1987) "Parametrization by non-linear regression and bayesian estimation of bentazepam in a multiple dosage regimen in humans". International Journal of Clinical Pharmacology, Therapy, and Toxicology 25 (11): 627–32. PMID 3429066.
- ↑ (September 1986) "Pharmacokinetics of tiadipone: a new anxiolytic". International Journal of Clinical Pharmacology, Therapy, and Toxicology 24 (9): 482–4. PMID 2877954.
- ↑ (November 1991) "Open-loop feedback control of serum bentazepam concentrations and Bayesian estimation in multiple dosage regimens in patients". International Journal of Clinical Pharmacology, Therapy, and Toxicology 29 (11): 457–62. PMID 1800395.
- ↑ (1989) "[Mixed benzodiazepine poisoning and reversal with flumazenil (Ro 15-1788)]". Revista Espanola de Anestesiologia y Reanimacion 36 (1): 48–50. PMID 2565591.
- ↑ (1990) "[A pharmacovigilance study with bentazepam in a sample of 1046 psychiatric outpatients]". Revista de Medicina de la Universidad de Navarra 34 (2): 80–8. PMID 1983365.
- ↑ (February 2003) "Collagenous and lymphocytic colitis. evaluation of clinical and histological features, response to treatment, and long-term follow-up". The American Journal of Gastroenterology 98 (2): 340–7. DOI:10.1111/j.1572-0241.2003.07225.x. PMID 12591052.
- ↑ (December 1997) "Bentazepam-induced hepatic bridging necrosis". Journal of Clinical Gastroenterology 25 (4): 710–1. DOI:10.1097/00004836-199712000-00042. PMID 9451703.
- ↑ (December 2006) "Outcome of acute idiosyncratic drug-induced liver injury: Long-term follow-up in a hepatotoxicity registry". Hepatology 44 (6): 1581–8. DOI:10.1002/hep.21424. PMID 17133470.
- ↑ Tuca (2003). "Utilidad clinica del acetato de megestrol para la ganancia de peso en los enfermos con neoplasia y caquexia" (in Spanish). Medicina Clinica 120 (17): 678. DOI:10.1157/13047309.
- ↑ (April 1994) "Bentazepam-associated chronic liver disease". Lancet 343 (8901): 860. DOI:10.1016/S0140-6736(94)92065-6. PMID 7908109.
- ↑ (July 2000) "Chronic liver injury related to use of bentazepam: an unusual instance of benzodiazepine hepatotoxicity". Digestive Diseases and Sciences 45 (7): 1400–4. DOI:10.1023/A:1005520523502. PMID 10961721.