Salicylamide (o-hydroxybenzamide or amide of salicyl) is a non-prescription drug with analgesic and antipyretic properties.[1] Its medicinal uses are similar to those of aspirin.[2] Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedy PainAid. It was also an ingredient in the over-the-counter pain remedy BC Powder but was removed from the formulation in 2009, and Excedrin used the ingredient from 1960 to 1980 in conjunction with aspirin, acetaminophen, and caffeine. It was used in later formulations of Vincent's powders in Australia as a substitute for phenacetin.
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| Clinical data | |
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| MedlinePlus | a681004 |
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| Pharmacokinetic data | |
| Excretion | Renal |
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| ECHA InfoCard | 100.000.554 |
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| Formula | C7H7NO2 |
| Molar mass | 137.138 g·mol−1 |
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| Density | 1.33 g/cm3 |
| Solubility in water | Soluble in hot water, ether, alcohol, and chloroform. mg/mL (20 °C) |
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Derivatives
editDerivatives of salicylamide include ethenzamide, labetalol, medroxalol, lopirin, otilonium, oxyclozanide, salicylanilide, niclosamide, and raclopride.
See also
editReferences
edit- ^ Borne R, Levi M, Wilson N (2008). "Nonsteroidal Anti-Inflammatory Drugs". In Foye WO, Williams DA (eds.). Foye's Principles of Medicinal Chemistry (6th ed.). Philadelphia London: Lippincott Williams & Wilkins. p. 968. ISBN 978-0-7817-6879-5.
- ^ "Salicylamide". Dictionary.com. Merriam-Webster's Medical Dictionary. Merriam-Webster, Inc. Retrieved December 31, 2006.
External links
edit- Safety MSDS data Archived 2016-03-03 at the Wayback Machine