Para-hydroxybenzoate—polyprenyltransferase, mitochondrial is an enzyme that in humans is encoded by the COQ2 gene .[ 5] [ 6]
CoQ (ubiquinone ) serves as a redox carrier in the mitochondrial respiratory chain and is a lipid-soluble antioxidant. COQ2, or parahydroxybenzoate-polyprenyltransferase (EC 2.5.1.39), catalyzes one of the final reactions in the biosynthesis of CoQ, the prenylation of parahydroxybenzoate with an all-trans polyprenyl group (Forsgren et al., 2004).[supplied by OMIM][ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000173085 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029319 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Forsgren M, Attersand A, Lake S, Grunler J, Swiezewska E, Dallner G, Climent I (Aug 2004). "Isolation and functional expression of human COQ2, a gene encoding a polyprenyl transferase involved in the synthesis of CoQ" . Biochem J . 382 (Pt 2): 519–26. doi :10.1042/BJ20040261 . PMC 1133808 PMID 15153069 . ^ a b "Entrez Gene: COQ2 coenzyme Q2 homolog, prenyltransferase (yeast)" .
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