CCNA2

CCNA2
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1E9H, 1FIN, 1FVV, 1GY3, 1H1P, 1H1Q, 1H1R, 1H1S, 1H24, 1H25, 1H26, 1H27, 1H28, 1JST, 1JSU, 1OGU, 1OI9, 1OIU, 1OIY, 1OKV, 1OKW, 1OL1, 1OL2, 1P5E, 1PKD, 1QMZ, 1URC, 1VYW, 2BKZ, 2BPM, 2C4G, 2C5N, 2C5O, 2C5V, 2C5X, 2C6T, 2CCH, 2CCI, 2CJM, 2I40, 2IW6, 2IW8, 2IW9, 2UUE, 2UZB, 2UZD, 2UZE, 2UZL, 2V22, 2WEV, 2WFY, 2WHB, 2WIH, 2WIP, 2WMA, 2WMB, 2WPA, 2WXV, 2X1N, 3EID, 3EJ1, 3EOC, 3F5X, 4BCK, 4BCM, 4BCN, 4BCP, 4CFM, 4CFN, 4CFU, 4CFV, 4CFW, 4CFX, 4EOI, 4EOJ, 4EOK, 4EOL, 4EOM, 4EON, 4EOO, 4EOP, 4EOQ, 4EOR, 4EOS, 4FX3, 5CYI, 5IF1
Dynodwyr
Cyfenwau	CCNA2, CCN1, CCNA, cyclin A2
Dynodwyr allanol	OMIM: 123835 HomoloGene: 55562 GeneCards: CCNA2
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0001948, GO:0016582 protein binding; • protein kinase binding; • cyclin-dependent protein kinase activity; • protein domain specific binding; • protein kinase activity; • cyclin-dependent protein serine/threonine kinase regulator activity;
Cydrannau o'r gell	• cytoplasm; • female pronucleus; • male pronucleus; • nucleoplasm; • cnewyllyn cell; • cyclin-dependent protein kinase holoenzyme complex; • cytosol; • cyclin A2-CDK2 complex;
Prosesau biolegol	• cochlea development; • cellular response to luteinizing hormone stimulus; • response to estradiol; • response to glucagon; • positive regulation of fibroblast proliferation; • cellular response to estradiol stimulus; • GO:1904579 cellular response to organic cyclic compound; • cellular response to insulin-like growth factor stimulus; • cellular response to platelet-derived growth factor stimulus; • cellular response to leptin stimulus; • Cellraniad; • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated; • animal organ regeneration; • cellular response to nitric oxide; • cell cycle; • Ras protein signal transduction; • GO:0022415 viral process; • cellular response to hypoxia; • adwaith y celloedd i gocên; • G2/M transition of mitotic cell cycle; • protein deubiquitination; • cell cycle G1/S phase transition; • regulation of cell cycle; • regulation of cyclin-dependent protein serine/threonine kinase activity; • GO:0007067 Mitosis; • regulation of DNA replication; • regulation of mitotic nuclear division; • positive regulation of cell population proliferation; • positive regulation of cell cycle;
	Sources:Amigo / QuickGO
Orthologau
	890
	n/a
	ENSG00000145386
	n/a
	P20248
	n/a
	NM_001237
	n/a
	NP_001228
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CCNA2 yw CCNA2 a elwir hefyd yn Cyclin A2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q27.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CCNA2.

CCN1
CCNA

Llyfryddiaeth

"Cyclin A2 as a potential differential marker of splenic diffuse red pulp small B-cell lymphoma: a report of the first case. ". Ann Hematol. 2017. PMID 27761608.
"Cyclin A predicts metastatic potential of rectal neuroendocrine tumors. ". Hum Pathol. 2014. PMID 24824027.
"CCNA2 is a prognostic biomarker for ER+ breast cancer and tamoxifen resistance. ". PLoS One. 2014. PMID 24622579.
"High expression of cyclin A is associated with poor prognosis in endometrial endometrioid adenocarcinoma. ". Tumour Biol. 2014. PMID 24519066.
"Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation.". Nature. 2013. PMID 24013174.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] CCNA2 - Cronfa NCBI

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[2]