S Wikipedije, slobodne enciklopedije
Protein DEPP poznat i kao materničnosluznički protein induciran progesteronom (DEPP) i genski protein induciran postom (FIG) je protein koji je kod ljudi kodiran genom DEPP .[ 5]
Dužina polipeptidnog lanca je 212 aminokiselina , а molekulska težina 23 406.[ 6]
10 20 30 40 50 MRSRLLLSVA HLPTIRETTE EMLLGGPGQE PPPSPSLDDY VRSISRLAQP TSVLDKATAQ GQPRPPHRPA QACRKGRPAV SLRDITARFS GQQPTLPMAD TVDPLDWLFG ESQEKQPSQR DLPRRTGPSA GLWGPHRQMD SSKPMGAPRG RLCEARMPGH SLARPPQDGQ QSSDLRSWTF GQSAQAMASR HRPRPSSVLR TLYSHLPVIH EL
Ekspresija ovog gena inducirana je postom kao i progesteronom . Protein kodiran ovim genom sadrži receptor proteina povezan s t-sinaptosomom (SNARE ) upredene zavojnice homolognog domena i peroksisomnom u signalu za ciljanje. Proizvodnja kodiranog proteina dovodi do fosforilacije i aktiviranja transkripcijskog faktora ELK1 .[ 5]
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination" . Genome Res . 10 (11): 1788–95. doi :10.1101/gr.143000 . PMC 310948 PMID 11076863 . Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline" . Genome Res . 14 (10B): 2136–44. doi :10.1101/gr.2576704 . PMC 528930 PMID 15489336 . Shin D, Anderson DJ (2005). "Isolation of arterial-specific genes by subtractive hybridization reveals molecular heterogeneity among arterial endothelial cells" . Dev. Dyn . 233 (4): 1589–604. doi :10.1002/dvdy.20479 PMID 15977181 . S2CID 20593942 . Watanabe H, Nonoguchi K, Sakurai T, et al. (2005). "A novel protein Depp, which is induced by progesterone in human endometrial stromal cells activates Elk-1 transcription factor" . Mol. Hum. Reprod . 11 (7): 471–6. doi :10.1093/molehr/gah186 PMID 16123073 . Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8. Bibcode :2005Natur.437.1173R . doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 . Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006" . Nucleic Acids Res . 34 (Database issue): D415–8. doi :10.1093/nar/gkj139 . PMC 1347501 PMID 16381901 . Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration" . Cell . 125 (4): 801–14. doi :10.1016/j.cell.2006.03.032 PMID 16713569 . S2CID 13709685 . 
