Enhancement of proteasome activity by a small-molecule inhibitor of USP14 (Q29616735)

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30 April 2017

11

Scott M. Wilson

1 reference

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10 July 2024

12

Randall W. King

1 reference

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10 July 2024

author name string

Lee BH

1

1 reference

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30 April 2017

Oh DC

4

1 reference

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30 April 2017

Chen PC

6

1 reference

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30 April 2017

Byung-Hoon Lee

1

1 reference

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10 July 2024

Min Jae Lee

2

1 reference

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10 July 2024

Soyeon Park

3

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10 July 2024

Dong-Chan Oh

4

1 reference

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10 July 2024

Suzanne Elsasser

5

1 reference

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10 July 2024

Ping-Chung Chen

6

1 reference

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Carlos Gartner

7

1 reference

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Nevena Dimova

8

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John Hanna

9

1 reference

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Steven P. Gygi

10

1 reference

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Daniel Finley

13

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10 July 2024

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30 April 2017

publication date

9 September 2010

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full work available at URL

30 April 2017

https://europepmc.org/articles/pmc2939003?pdf=render

online access status

open access

1 reference

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20829789/?tool=EBI

10 July 2024

1 reference

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10 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20829789

https://europepmc.org/articles/PMC2939003

10 July 2024

1 reference

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10 July 2024

online access status

open access

content deliverer

1 reference

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http://www.nature.com/articles/nature09299.pdf

10 July 2024

https://api.crossref.org/works/10.1038/NATURE09299

1 reference

http://www.nature.com/articles/nature09299

10 July 2024

1 reference

https://api.crossref.org/works/10.1038/NATURE09299

10 July 2024

1 reference

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30 April 2017

volume

467

1 reference

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30 April 2017

issue

7312

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30 April 2017

page(s)

179-84

1 reference

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Targeting proteins for degradation

30 April 2017

cites work

1 reference

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The ubiquitin proteasome system in neuropathology

30 April 2017

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Recognition and processing of ubiquitin-protein conjugates by the proteasome

30 April 2017

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Proteasome subunit Rpn13 is a novel ubiquitin receptor

30 April 2017

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Adapting proteostasis for disease intervention

30 April 2017

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Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome

30 April 2017

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Mass spectrometric characterization of the affinity-purified human 26S proteasome complex

30 April 2017

1 reference

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hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37

30 April 2017

1 reference

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Transgenic rescue of ataxia mice with neuronal-specific expression of ubiquitin-specific protease 14

30 April 2017

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Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation.

30 April 2017

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A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes

30 April 2017

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Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14

30 April 2017

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CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation

30 April 2017

1 reference

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Protein degradation and protection against misfolded or damaged proteins

30 April 2017

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Multiple associated proteins regulate proteasome structure and function

30 April 2017

1 reference

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Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease

30 April 2017

1 reference

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A cryptic protease couples deubiquitination and degradation by the proteasome

30 April 2017

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Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome

30 April 2017

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A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14

30 April 2017

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Analysis of the deubiquitinating enzymes of the yeast Saccharomyces cerevisiae

30 April 2017

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Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes

30 April 2017

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Recognition of the polyubiquitin proteolytic signal

30 April 2017

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Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome

30 April 2017

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Ubiquitinated proteins activate the proteasome by binding to Usp14/Ubp6, which causes 20S gate opening

30 April 2017

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The lysine 48 and lysine 63 ubiquitin conjugates are processed differently by the 26 s proteasome

3 June 2018

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The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions

3 June 2018

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Ubiquitin degradation with its substrate, or as a monomer in a ubiquitination-independent mode, provides clues to proteasome regulation

3 June 2018

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Tau pathophysiology in neurodegeneration: a tangled issue

3 June 2018

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Targeting the UPS as therapy in multiple myeloma

3 June 2018

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Transgenic rescue of ataxia mice reveals a male-specific sterility defect

3 June 2018

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TDP-43 proteinopathies: neurodegenerative protein misfolding diseases without amyloidosis

3 June 2018

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Protein oxidative modifications and replicative senescence of WI-38 human embryonic fibroblasts.

3 June 2018

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Cellular turnover of the polyglutamine disease protein ataxin-3 is regulated by its catalytic activity

3 June 2018

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Screen for ISG15-crossreactive deubiquitinases

3 June 2018

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Chaperones and proteases: cellular fold-controlling factors of proteins in neurodegenerative diseases and aging.

3 June 2018

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Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1.

3 June 2018

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Ubiquitin depletion as a key mediator of toxicity by translational inhibitors

3 June 2018

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Felix Hoppe-Seyler Lecture 2000. The ubiquitin system and the N-end rule pathway

3 June 2018

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A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis.

3 June 2018

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Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process

26 November 2018

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A ubiquitin stress response induces altered proteasome composition.

26 November 2018

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Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology

26 November 2018

1 reference

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Probing the ubiquitin/proteasome system with ornithine decarboxylase, a ubiquitin-independent substrate

26 November 2018

1 reference

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Loss of Usp14 results in reduced levels of ubiquitin in ataxia mice

26 November 2018

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Pleiotropic effects of Ubp6 loss on drug sensitivities and yeast prion are due to depletion of the free ubiquitin pool

26 November 2018

1 reference

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Proteasomal degradation of tau protein

26 November 2018

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Short-lived green fluorescent proteins for quantifying ubiquitin/proteasome-dependent proteolysis in living cells

26 November 2018

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12 December 2020

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7 January 2021

Overexpression of proteasome beta5 assembled subunit increases the amount of proteasome and confers ameliorated response to oxidative stress and higher survival rates

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12 December 2020

Preparation of ubiquitinated substrates by the PY motif-insertion method for monitoring 26S proteasome activity

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Protein oxidation and aging

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Defining the human deubiquitinating enzyme interaction landscape

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7 January 2021

Characterization of the proteasome using native gel electrophoresis

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7 January 2021

Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites.

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7 January 2021

A multimeric assembly factor controls the formation of alternative 20S proteasomes

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7 January 2021

Hexameric assembly of the proteasomal ATPases is templated through their C termini

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7 January 2021

Statistical practice in high-throughput screening data analysis

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7 January 2021

Hrs, a mammalian master molecule in vesicular transport and protein sorting, suppresses the degradation of ESCRT proteins signal transducing adaptor molecule 1 and 2

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7 January 2021

The role of autophagy during the early neonatal starvation period

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7 January 2021

Methods in mammalian autophagy research

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7 January 2021

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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7 January 2021

Single-step procedure for labeling DNA strand breaks with fluorescein- or BODIPY-conjugated deoxynucleotides: detection of apoptosis and bromodeoxyuridine incorporation.

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7 January 2021

Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation.

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7 January 2021

Antioxidants Enhance Mammalian Proteasome Expression through the Keap1-Nrf2 Signaling Pathway

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62

51

2212

MA Jordan

1991

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20829789

10 July 2024

Identifiers

2 references

30 April 2017

Dimensions Publication ID

1010359242

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20829789

2 references

30 April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20829789

2 references

30 April 2017