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The microbiome comprises all of the genetic material within a microbiota (the entire collection of microorganisms in a specific niche, such as the human gut). This can also be referred to as the metagenome of the microbiota.
Lactobacilli are a principal microbial constituent in the human uterine cervix and vagina. Here, authors identify the stem cells in the human uterine cervix and the role of Lactobacilli metabolite in cervical stem cells and cervical cancers.
Determinants of soil microbial community structure are less well studied. Here, Riddley et al. profile nationwide bacterial biogeographic patterns, and identify key environmental factors and distinct roles of deterministic and stochastic processes in shaping ecotype community assembly across terrestrial ecosystems.
The PI3K-Akt signaling pathway of the microbiotagut-brain axis is involved in forced loss induced by forced reduction of social rank in mice, and influences the outcome of forced loss.
Microbial community analysis of rhizospheric and phyllospheric microbiota transplantation to induce Cotton Leaf Curl Disease tolerance in Gossypium hirsutum, with transcriptomic examination post-transplantation from Gossypium arboreum.
A diet ‘restoration’ strategy that mimics non-industrialized dietary habits showed beneficial effects on the gut microbiome that were predictive of cardiometabolic benefits.
In this study, Li et al. perform a randomized controlled feeding trial to test the effects of a microbiome restoration strategy on gut microbiome features, host physiology and health.