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Focus on cell death
Our understanding of distinct and diverse modes of cell death and their contributions to homeostasis and disease has significantly progressed in recent years. In this Focus, we highlight exciting advances in this field with commissioned content, an Editorial, Research Highlights and a selection of related research articles published by Nature Cell Biology.
Image: Andrew J. Davidson, University of Glasgow -
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Innovations in Stem Cell Biology 2024
From the generation of embryo-like structures to the establishment of cell-based approaches to model or treat disease, the field of stem cell and developmental biology has impressively progressed during the past few months.
Image: Jacob Hanna and Maayan Visuals – Oldak B. et al. Complete human day 14 post-implantation embryo models from naive ES cells. Nature 622, 562–573 (2023). https://www.nature.com/articles/s41586-023-06604-5 -
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Celebrating 25 years of cell biology
2024 marks twenty five years since the launch of Nature Cell Biology.
Image: CHRISTOPH BURGSTEDT/SCIENCE PHOTO LIBRARY/Getty -
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Human BioMolecular Atlas Program
Inaugurated in 2018, the Human BioMolecular Atlas Program (HuBMAP) endeavours to construct comprehensive spatial maps that feature a range of biomolecules such as RNA, proteins, and metabolites in human organs at single-cell resolution.
Image: Heidi Schlehlein -
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Innovations in Stem Cell Biology 2023
Stem cell models of development, regeneration, and disease are quickly advancing. New technologies and concepts are continuously combined with existing knowledge to create more realistic systems to improve our understanding of these intricate processes. In this collection, we highlight papers published in 2022-2023 across Nature Portfolio journals on topics including embryonic development and stem cells, reproductive biology, synthetic tissues and embryo models, clinical and translational research and tissue stem cells.
Image: Jean-Baptiste Sibarita, Virgile Viasnoff, and Anne Beghin -
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Cancer research
Cancer is a leading cause of death, accounting for nearly one in six deaths worldwide. Many cancers can be cured, especially if detected early and treated effectively.
Image: Kateryna Lon/ Science Photo Library/ Getty Images -
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Extracellular vesicles
Selected, recent articles from across the Nature Portfolio that document the recent progress in understanding the biology of EV-mediated cell–cell communication and advances in clinical translation of EVs.
Image: Vicky Summersby -
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Genome editing
This Collection provides an overview of current progress in developing targeted genome editing technologies, including a selection of protocols for using and adapting these tools in your own lab.
Image: LuckyStep48 / Alamy Stock Vector -
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Cell cycle
One of the fundamental biological processes in life is the cell cycle leading from DNA replication to cell division. While it has been studied for decades and our knowledge has matured, sophisticated experimental approaches have rejuvenated the field. In addition, cell cycle regulators have emerged as cancer therapy targets. This collection showcases ground-breaking cell cycle papers and reviews, ranging from basic discoveries to clinical applications.
Image: Nicolas Plachta, NCB (2022) -
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Methods for studying non-coding RNA
Research interest is growing in profiling noncoding RNAs and understanding their biological functions in health and disease contexts.
Image: Jeren (France) / Getty Images -
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Mapping the cells of the body
In this Focus, we highlight progress in the use of single-cell technologies to analyze large datasets to map cellular diversity in entire organisms, examine cell types and states, cellular interactions and functions.
Image: Image courtesy of Genome Research Limited