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Hans Tuppy

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Hans Tuppy
Born(1924-07-22)22 July 1924
Vienna, Austria
Died24 April 2024(2024-04-24) (aged 99)
Alma materUniversity of Vienna
Known forInsulin sequencing
AwardsSchrödinger Prize
Wilhelm Exner Medal (1978).[1]
Scientific career
FieldsBiochemistry, protein structure
InstitutionsCambridge University, University of Vienna
Doctoral advisorErnst Späth, Friedrich Galinovsky

Hans Tuppy (22 July 1924 – 24 April 2024) was an Austrian biochemist who participated in the sequencing of insulin, and became Austria's first university professor for biochemistry. He was Austrian Minister for Science and Research from 1987 to 1989.

Background

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Hans Tuppy's parents were from the present day Czech Republic, his mother Emma from Prague and his father Karl from Brünn. Karl Tuppy (1 January 1880 – 15 November 1939) was chief prosecutor in the trial against those members of the illegal Austrian Nazi party who had murdered chancellor Engelbert Dollfuss during the abortive 1934 July Putsch. After Austria's Anschluss Karl Tuppy was detained and eventually moved to the Sachsenhausen concentration camp, where he was so savagely beaten upon his arrival that he died the following night.[2] While Hans Tuppy's older brother Peter was killed in action as a Wehrmacht soldier in 1944, Hans (who completed secondary school in 1942) was ordered into the Reichsarbeitsdienst (RAD) but was soon released from duty after suffering a severe injury.

Tuppy died on 24 April 2024, at the age of 99. His death was announced on 8 May.[3]

Career

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Tuppy was able to start studying at the University of Vienna even before World War II ended in Austria, thanks to his early release from RAD service. He completed the requirements for his diploma in 1945 and began his doctoral work in the laboratory of Professor Ernst Späth. However, after Späth passed away in 1946, Tuppy continued his research under the guidance of Friedrich Galinovsky and earned his Ph.D. degree in 1948.

Shortly thereafter Professor Frederick Wessely, Director of the Chemistry Institute recommended Tuppy to Max Perutz for postdoctoral work at Cambridge University. Perutz, in turn, recommended Tuppy to Frederick Sanger. Thus Tuppy joined Sanger's laboratory at Cambridge where he worked on the amino acid sequence of bovine insulin, sequencing its beta chain[4] (Sanger was awarded the Nobel Prize in 1958 for sequencing insulin).

Tuppy's next career step was the Carlsberg Laboratory in Copenhagen, from where he returned to the University of Vienna in 1951 to become an assistant at the Institute for Chemistry II. In 1956 he completed the Habilitation, the highest academic qualification in the Austrian academic system which qualifies the recipient to supervise doctoral students and, ultimately, to hold senior faculty positions. In 1963, Tuppy became Professor of Biochemistry in the Institute of Biochemistry at the University of Vienna. In 1973, he received the Schrödinger Prize of the Austrian Academy of Sciences.

During his distinguished career, Tuppy was President of the Austrian Science Fund (1974–1982), Rector of the University of Vienna (1983–1985), President of the Austria Academy of Sciences (1985–1987) and the Austrian Government Minister for Science and Research (1987–1989) during the chancellorship of Franz Vranitzky. He was chair of the university board of the University of Natural Resources and Applied Life Sciences Vienna from 2003.

Honours and awards

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References

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  1. ^ Editor, ÖGV. (2015). Wilhelm Exner Medal. Austrian Trade Association. ÖGV. Austria.
  2. ^ Wantoch, E.: Tuppys Ermordung. Eine Rekonstruktion. Teil II: Die Tat. profil No. 28, 13 July 1987, p. 46–51 (An eyewitness account of Karl Tuppy's murder)
  3. ^ "Biochemiker Hans Tuppy 99-jährig verstorben". science.ORF.at (in German). 8 May 2024. Retrieved 8 May 2024.
  4. ^ Sanger F, Tuppy H (1951). "The Amino-acid Sequence in the Phenylalanyl Chain of Insulin. I. The identification of lower peptides from partial hydrolysates". Biochemical Journal. 49 (4): 463–81. doi:10.1042/bj0490463. PMC 1197535. PMID 14886310.
  5. ^ "Reply to a parliamentary question" (PDF) (in German). p. 426. Retrieved 24 November 2012.
  6. ^ "Website of the Austrian Academy of Sciences" (in German). Retrieved 22 May 2024.
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See also: Tuppy, Tupý, and Tupy (disambiguation)
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