Centrosomal protein 85

CEP85
Identifiers
Aliases	CEP85, CCDC21, centrosomal protein 85
External IDs	MGI: 1917262; HomoloGene: 11254; GeneCards: CEP85; OMA:CEP85 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	26,278,808 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	134,187,112 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; Skeletal muscle tissue of rectus abdominis; ; muscle of thigh; ; thoracic diaphragm; ; gastrocnemius muscle; ; apex of heart; ; vastus lateralis muscle; ; gonad; ; muscle of arm;
	Top expressed in
	right kidney; ; spermatocyte; ; muscle of thigh; ; thymus; ; neural layer of retina; ; yolk sac; ; proximal tubule; ; otic vesicle; ; zygote; ; spermatid;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	centrosome; Golgi apparatus; spindle pole; pericentriolar material; nucleolus; cytoskeleton; nucleus; cytoplasm; cytosol; mitochondrion; microtubule organizing center;
Biological process	regulation of mitotic centrosome separation; negative regulation of protein kinase activity; chromosome segregation;
	Sources:Amigo / QuickGO
Orthologs
	64793
	70012
	ENSG00000130695
	ENSMUSG00000037443
	Q6P2H3
	Q8BMK0
	NM_001281517; NM_001281518; NM_022778; NM_001319944
	NM_144527
	NP_001268446; NP_001268447; NP_001306873; NP_073615
	NP_653110
	Wikidata
View/Edit Human	View/Edit Mouse

Centrosomal protein 85 is a protein that in humans is encoded by the CEP85 gene. ^[5]

Function

This gene encodes a protein that belongs to the centrosome-associated family of proteins. The centrosome is a subcellular organelle in the animal cell that functions as a microtubule organizing center and is involved in cell-cycle progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000130695 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000037443 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Centrosomal protein 85". Retrieved 2018-06-01.

Function

References

Further reading