TRNK nukleotidiltransferaza
(Preusmjereno sa stranice RNaza PH)
| TRNK nukleotidiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Heksamer RNaze PH (Pseudomonas aeruginosa) | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.7.7.56 | ||||||||
| CAS broj | 116412-36-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
TRNK nukleotidiltransferaza (EC 2.7.7.56, fosfat-zavisna eksonukleaza, RNaza PH, ribonukleaza PH) je enzim sa sistematskim imenom tRNK:fosfat nukleotidiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- tRNKn+1 + fosfat tRNKn + nukleozid difosfat
Ovaj enzim vrši finalno eksonukleolitičko odsecanje na 3'-terminusu tRNK prekursora kod Escherichia coli putem fosforolize.
- ↑ Cudny, H. and Deutscher, M.P. (1988). „3′ processing of tRNA precursors in ribonuclease-deficient Escherichia coli. Development and characterization of an in vitro processing system and evidence for a phosphate requirement”. J. Biol. Chem. 263: 1518-1523. PMID 3275667.
- ↑ Deutscher, M.P., Marshall, G.T. and Cudny, H. (1988). „RNase PH: an Escherichia coli phosphate-dependent nuclease distinct from polynucleotide phosphorylase”. Proc. Natl. Acad. Sci. USA 85: 4710-4714. PMID 2455297.
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