Whole genome amplification of sodium bisulfite-treated DNA allows the accurate estimate of methylated cytosine density in limited DNA resources
J Mill, S Yazdanpanah, E Gückel, S Ziegler… - …, 2006 - Taylor & Francis
Sodium bisulfite modification-based fine mapping of methylated cytosines represents the
gold standard technique for DNA methylation studies. A major problem with this approach, …
gold standard technique for DNA methylation studies. A major problem with this approach, …
Identification of Terfenadine as an Inhibitor of HumanCD81-Receptor HCV-E2 Interaction: Synthesis and Structure Optimization
M Holzer, S Ziegler, B Albrecht, B Kronenberger… - Molecules, 2008 - mdpi.com
Terfenadine (4-[4-(hydroxydiphenylmethyl)-1-piperidyl]-1-(4-tert-butyl-phenyl)-butan-1-ol) was
identified in a biological screening to be a moderate inhibitor (27 % inhibition) of the CD81…
identified in a biological screening to be a moderate inhibitor (27 % inhibition) of the CD81…
Structural Modifications of Salicylates: Inhibitors of Human CD81‐Receptor HCV‐E2 Interaction
M Holzer, S Ziegler, A Neugebauer… - … der Pharmazie: An …, 2008 - Wiley Online Library
Starting point of the present paper was the result of a virtual screening using the open
conformation of the large extracellular loop (LEL) of the CD81‐receptor (crystal structure: PDB‐ID: …
conformation of the large extracellular loop (LEL) of the CD81‐receptor (crystal structure: PDB‐ID: …
Development and evaluation of a FACS-based medium-throughput assay for HCV entry inhibitors
S Ziegler, B Kronenberger, BAM Albrecht, A Kaul… - SLAS Discovery, 2009 - Elsevier
The interaction between the hepatitis C virus (HCV) envelope glycoprotein E2 and the human
tetraspanin protein CD81 is one of the key events involved in HCV cell entry. Therefore, …
tetraspanin protein CD81 is one of the key events involved in HCV cell entry. Therefore, …
Microwave-assisted syntheses of amino acid ester substituted benzoic acid amides: potential inhibitors of human CD81-receptor HCV-E2 interaction
M Holzer, S Ziegler, B Kronenberger… - The open medicinal …, 2008 - pmc.ncbi.nlm.nih.gov
Results from our group showed benzyl salicylate to be a moderate inhibitor of the CD81-LEL–HCV-E2
interaction. To increase the biological activity, heterocyclic substituted benzoic …
interaction. To increase the biological activity, heterocyclic substituted benzoic …
Präklinische Wirkstoffentwicklung: Assays zur Bewertung von Hemmstoffen des Hepatitis C Virus Eintritts sowie von Inhibitoren der Acetylcholinesterase und der …
S Ziegler - 2008 - publikationen.sulb.uni-saarland.de
Weltweit sind 300 Millionen Menschen mit dem Hepatitis C Virus infiziert. Die gängige Therapie
aus Ribavirin und Interferon greift in weniger als 60 % aller Fälle. Die Schlüsselproteine …
aus Ribavirin und Interferon greift in weniger als 60 % aller Fälle. Die Schlüsselproteine …
[TRÍCH DẪN][C] Epigenomic microarray profiling of DNA methylation variability in monozygotic and dizygotic twins
Z Kaminsk, SC Wang, S Ziegler… - … Journal of Medical …, 2006 - espace.library.uq.edu.au
Sigrid Albert, Bellum iustum. Die Theorie des „gerechten Krieges" und ihre praktische Bedeutung für die auswärtigen Auseinandersetzungen Roms in …
KH Ziegler - Zeitschrift der Savigny-Stiftung für Rechtsgeschichte …, 1982 - degruyter.com
1. Mit der vorliegenden Arbeit, der überarbeiteten Fassung einer von Helga Gesche betreuten
althistorischen Dissertation, wird ein zentraler Begriff des antiken römischen Völkerrechts …
althistorischen Dissertation, wird ein zentraler Begriff des antiken römischen Völkerrechts …
The openness-fluid-crystallized-intelligence (OFCI) model and the environmental enrichment hypothesis
The Openness-Fluid-Crystallized-Intelligence (OFCI) model describes how these different
constructs interact over time. One fundamental element in the model is the Environmental …
constructs interact over time. One fundamental element in the model is the Environmental …
[TRÍCH DẪN][C] Die Temperaturkorrektur der Säure-Basen-Parameter bei Frühgeborenen
S Ziegler - 1969