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The influence of codon context on genetic code translation

Nature volume 286, pages 123–127 (1980)Cite this article

Abstract

A class of mutations that increase the efficiency of a suppressor tRNA in translating a particular amber codon has been characterized. The increased efficiency is due to a mutation resulting in a change in the mRNA that affects the nucleotide adjacent to the 3′ side of the UAG triplet. Thus the interaction of tRNA with mRNA is influenced by mRNA sequences outside the triplet codon.

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Author notes

  1. Lionello Bossi

    Present address: European Molecular Biology Laboratory, Heidelberg, FRG

Authors and Affiliations

  1. Department of Biology, University of Utah, Salt Lake City, Utah, 84112

    Lionello Bossi & John R. Roth

  2. I Istituto di Chimica Biologica, Il Facolta' di Medicina e Chirurgia, University of Naples, Italy

    Lionello Bossi

Authors
  1. Lionello Bossi
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  2. John R. Roth
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Bossi, L., Roth, J. The influence of codon context on genetic code translation. Nature 286, 123–127 (1980). https://doi.org/10.1038/286123a0

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