Interleukin 18 receptor 1 (Q21495874)

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mammalian protein found in Mus musculus

IL-18R-alpha
interleukin-18 receptor 1
IL-18R-1
IL1R-rp
IL1 receptor-related protein
IL-18Ralpha
CD218 antigen-like family member A
IL-1Rrp
interleukin 1 receptor related protein
interleukin-18 receptor alpha
Il18r1
IL-18R1

Language	Label	Description	Also known as
English	Interleukin 18 receptor 1	mammalian protein found in Mus musculus	IL-18R-alpha interleukin-18 receptor 1 IL-18R-1 IL1R-rp IL1 receptor-related protein IL-18Ralpha CD218 antigen-like family member A IL-1Rrp interleukin 1 receptor related protein interleukin-18 receptor alpha Il18r1 IL-18R1

Statements

1 reference

25 May 2022

UniProt protein ID

interleukin-1 receptor family

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61098

Immunoglobulin-like fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61098

Immunoglobulin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61098

Toll/interleukin-1 receptor homology (TIR) domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61098

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Immunoglobulin subtype, protein family

1 reference

based on heuristic

inferred from protein domain or family

Toll/interleukin-1 receptor homology (TIR) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

immunoglobulin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

interleukin-18 receptor activity

determination method or standard

1 reference

1 January 2018

Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61098&geneProductId=UniProtKB:Q61098

determination method or standard

protein binding

determination method or standard

1 reference

9 May 2019

Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

interleukin-18 binding

determination method or standard

interleukin-18 receptor activity

determination method or standard

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

14 February 2019

Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

interleukin-18 binding

determination method or standard

4 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

interleukin-18 receptor activity

determination method or standard

4 references

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

9 May 2019

Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

integral component of membrane

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

interleukin-18 receptor complex

determination method or standard

1 reference

14 January 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61098&geneProductId=UniProtKB:Q61098

determination method or standard

biological process

natural killer cell activation

determination method or standard

1 reference

9 May 2019

Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

positive regulation of interferon-gamma production

determination method or standard

1 reference

27 March 2018

Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61098&geneProductId=UniProtKB:Q61098

determination method or standard

T-helper 1 cell differentiation

determination method or standard

1 reference

9 May 2019

Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

signal transduction

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

interleukin-18-mediated signaling pathway

determination method or standard

1 reference

27 March 2018

Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61098&geneProductId=UniProtKB:Q61098

determination method or standard

positive regulation of NIK/NF-kappaB signaling

determination method or standard

1 reference

9 May 2019

Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

positive regulation of interferon-gamma production

determination method or standard

3 references

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61098&geneProductId=UniProtKB:Q61098

determination method or standard

5 June 2018

Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61098&geneProductId=UniProtKB:Q61098

determination method or standard

5 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61098&geneProductId=UniProtKB:Q61098

determination method or standard

interleukin-18-mediated signaling pathway

determination method or standard

3 references

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61098&geneProductId=UniProtKB:Q61098

determination method or standard

5 June 2018

Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61098&geneProductId=UniProtKB:Q61098

determination method or standard

5 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61098&geneProductId=UniProtKB:Q61098

determination method or standard

inflammatory response

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

positive regulation of interferon-gamma production

determination method or standard

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

14 February 2019

Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

interleukin-18-mediated signaling pathway

determination method or standard

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

14 February 2019

Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

positive regulation of NF-kappaB transcription factor activity

determination method or standard

negative regulation of cold-induced thermogenesis

determination method or standard

1 reference

9 May 2019

Divergent responses to thermogenic stimuli in BAT and subcutaneous adipose tissue from interleukin 18 and interleukin 18 receptor 1-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

positive regulation of T-helper 1 cell cytokine production

determination method or standard

positive regulation of interferon-gamma production

determination method or standard

5 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

9 May 2019

Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

interleukin-18-mediated signaling pathway

determination method or standard

5 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

9 May 2019

Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61098

determination method or standard

immunoglobulin subtype

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61098

Toll/interleukin-1 receptor homology (TIR) domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61098

immunoglobulin-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61098

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000085298

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000085298

ENSMUSP00000103679

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000103679

ENSMUSP00000142070

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000142070

ENSMUSP00000128277

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000128277

ENSMUSP00000141464

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000141464

ENSMUSP00000141695

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000141695

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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