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Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 Å Resolution

Nature volume 206, pages 757–761 (1965)Cite this article

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References

  1. Fleming, A., Proc. Roy. Soc., B, 93, 306 (1922).

    Article  ADS  CAS  Google Scholar 

  2. Jollès, J., Jauregui-Adell, J., and Jollès, P., Biochim. Biophys. Acta, 78, 68 (1963).

    Google Scholar 

  3. Jollès, P., Jauregui-Adell, J., and Jollès, J., C.R. Acad. Sci., Paris, 258, 3926 (1964).

    Google Scholar 

  4. Canfield, R. E., J. Biol. Chem., 238, 2698 (1963).

    CAS  PubMed  Google Scholar 

  5. Canfield, R. E., and Liu, A. K., J. Biol. Chem. (in the press).

  6. Brown, J. R., Biochem. J., 92, 13P (1964).

    Google Scholar 

  7. Johnson, L. N., and Phillips, D. C. (following article).

  8. Alderton, G., and Fevold, J., J. Biol. Chem., 164, 1 (1946).

    CAS  PubMed  Google Scholar 

  9. Palmer, K. J., Ballantyre, M., and Galvin, J. A., J. Amer. Chem. Soc., 70, 906 (1948).

    Article  CAS  Google Scholar 

  10. Steinrauf, L. K., Acta Cryst., 12, 77 (1959).

    Article  CAS  Google Scholar 

  11. Blake, C. C. F., Fenn, R. H., North, A. C. T., Phillips, D. C., and Poljak, R. J., Nature, 196, 1173 (1962).

    Article  ADS  CAS  PubMed  Google Scholar 

  12. Holmes, K. C., and Leberman, R., J. Mol. Biol., 6, 439 (1963).

    Article  CAS  PubMed  Google Scholar 

  13. Poljak, R. J., J. Mol. Biol., 6, 244 (1963).

    Article  CAS  PubMed  Google Scholar 

  14. Arndt, U. W., and Phillips, D. C., Acta Cryst., 14, 807 (1961).

    Article  CAS  Google Scholar 

  15. Phillips, D. C., J. Sci. Instrum., 41, 123 (1964).

    Article  ADS  Google Scholar 

  16. Arndt, U. W., North, A. C. T., and Phillips, D. C., J. Sci. Instrum., 41, 421 (1964).

    Article  ADS  Google Scholar 

  17. Blow, D. M., and Crick, F. H. C., Acta Cryst., 12, 794 (1959).

    Article  CAS  Google Scholar 

  18. North, A. C. T., Acta Cryst., 18, 212 (1965).

    Article  CAS  Google Scholar 

  19. Crick, F. H. C., and Magdoff, B. S., Acta Cryst., 9, 901 (1956).

    Article  CAS  Google Scholar 

  20. Hamilton, W. C., Rollett, J. S., and Sparks, R. A., Acta Cryst., 18, 129 (1965).

    Article  Google Scholar 

  21. North, A. C. T., Phillips, D. C., and Mathews, F. S. (in preparation).

  22. Hart, R. G., Acta Cryst., 14, 1188 (1961).

    Article  Google Scholar 

  23. Blake, C. C. F., Fenn, R. H., and Phillips, D. C. (in preparation).

  24. Kendrew, J. C., Dickerson, R. E., Strandberg, B. E., Hart, R. G., Davies, D. R., Phillips, D. C., and Shore, V. C., Nature, 185, 422 (1960).

    Article  ADS  CAS  PubMed  Google Scholar 

  25. Kendrew, J. C., Watson, H. C., Strandberg, B. E., Dickerson, R. E., Phillips, D. C., and Shore, V. C., Nature, 190, 663 (1961).

    Article  ADS  Google Scholar 

  26. Urnes, P., and Doty, P., Adv. Prot. Chem., 16, 401 (1961).

    CAS  Google Scholar 

  27. Hamaguchi, K., and Imahori, K., J. Biochem. (Japan), 55, 388 (1964).

    Article  CAS  PubMed  Google Scholar 

  28. Kendrew, J. C., Brookhaven Symp. Quant. Biol., 15, 216 (1962).

    CAS  Google Scholar 

  29. Kravchenko, N. A., Kleopina, G. V., and Kaverzneva, E. D., Biochim. Biophys. Acta, 92, 412 (1964).

    CAS  PubMed  Google Scholar 

  30. Bernier, I., and Jollès, P., C.R. Acad. Sci., Paris, 253, 745 (1961).

    CAS  Google Scholar 

  31. Ramachandran, L. K., and Rao, G. J. S., Biochim. Biophys. Acta, 59, 507 (1962).

    Article  PubMed  Google Scholar 

  32. Hartdegen, F. J., and Rupley, J. A., Biochim. Biophys. Acta, 92, 625 (1964).

    CAS  PubMed  Google Scholar 

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Author notes

  1. D. F. KOENIG

    Present address: Brookhaven National Laboratory, Upton, Long Island, New York

  2. A. C. T. NORTH and D. C. PHILLIPS: Medical Research Council External Staff.

Authors and Affiliations

  1. Davy Faraday Research Laboratory, Royal Institution, 21 Albemarle Street, London, W.1

    C. C. F. BLAKE,  D. F. KOENIG,  G. A. MAIR,  A. C. T. NORTH,  D. C. PHILLIPS &  V. R. SARMA

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  1. C. C. F. BLAKE
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  5. D. C. PHILLIPS
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  6. V. R. SARMA
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BLAKE, C., KOENIG, D., MAIR, G. et al. Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 Å Resolution. Nature 206, 757–761 (1965). https://doi.org/10.1038/206757a0

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