The first feature film to use the Arri Alexa M camera.
Kathy Bates was originally cast as Ms. Jibsen, but dropped out due to health concerns and was replaced by Judy Davis.
Jean-Pierre Jeunet's second English-language movie, following Quái Vật Không Gian 4: Hồi Sinh (1997) which was a Hollywood production; The Young and Prodigious T.S. Spivet was a French-Canadian co-production.
Tapioca the dog is named after one of the movies' production companies.