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The show's creator, Stephen Hillenburg, was a marine biologist. When he pitched the show to Nickelodeon, he brought a fish tank into the boardroom, and explained what was living inside. He then placed a cartoon drawing of SpongeBob into the tank and said "This is SpongeBob, the star of your new show."

Plankton's size varies throughout the series.

The background of the end credits shows white silhouettes of flowers upon a yellow background. The music that plays usually is the closing theme, which is ukulele music.

The French version digitally changes the opening title cards for each episode to the title in French. The opening sequence has also been slightly altered: the bubble words "SpongeBob SquarePants" has been replaced with a bubble version of SpongeBob. On the board that changes colors, SpongeBob's face replaces the name SpongeBob SquarePants; the part where SpongeBob's pants bounce around the show's title has been replaced with scenery in Bikini Bottom, and the show's title is digitally altered to read "Bob l'eponge".

Featured in Everybody's Talking: The Voices of Spongebob Squarepants (2003)