- He was actually behind the wheel of the taxicab that drives across the bridge during the opening credits of every episode of Taxi (1978).
- Before he starred on Taxi (1978), he was a boxer and was still fighting professionally during the first few seasons.
- Teaching a 10th-grade English class at Northeast High School in Philadelphia, Pennsylvania. (April 2010)
- Wrote to the late Tupac Shakur while he was in prison. The two later became friends.
- His acting mentor was Judd Hirsch.
- In 1993, he broke his back skiing in Utah, and had plates, rods, and screws in his spine. He lost his house in the Northridge earthquake on January 17, 1994.
- Tony Micelli, Danza's character on Who's the Boss? (1984), was ranked #23 in TV Guide's list of the "50 Greatest TV Dads of All Time" [20 June 2004 issue].
- Retired from boxing following his third-round knockout victory over Johnny Heard on May 5, 1979 in Phoenix, Arizona.
- Made his professional boxing debut on August 3, 1976 by knocking out Earl Harris in the first round.
- His first "Hollywood girlfriend" was Taxi (1978) co-star Marilu Henner.
- Received his Bachelor of Arts degree in history from the University of Dubuque (1972), which he attended on a wrestling scholarship.
- His character Tony Banta on Taxi (1978) was originally named Phil Banta, but the producers changed it to his real-life name thinking that the inexperienced actor wouldn't respond to the name Phil.
- On September 9, 1977, he was knocked down by Ralph "Rocky" Garcia, but climbed off the canvas to knock out Garcia in the first round.
- Became a grandfather for the first time on August 27, 2005 when his son Marc Anthony Danza and daughter-in-law Julie, both 34, welcomed son Nicholas David.
- Tony's son, Marc Anthony Danza, appeared on two episodes of Taxi (1978) portraying a foster child that Tony wanted to adopt.
- Danza, a racehorse named for the actor, finished third in the 2014 Kentucky Derby. Danza attended as an invited guest of the horse's owners, who had been attracted to him and his name from his sitcom Who's the Boss? (1984).
- Was one of three cast members to appear in all 196 episodes of Who's the Boss? (1984). Was also one of four cast members to appear in all 114 episodes of Taxi (1978).
- Was the only then-living regular cast member of Taxi (1978) not to appear in Man on the Moon (1999), on account of other commitments he had. The film had most of the cast members appearing as their younger selves.
- Has two daughters with ex-wife Tracy Robinson: Katherine Danza (born 1987) and Emily Danza (born 1993).
- Has two children with ex-wife Rhonda "Yeoman" Iadanza: Marc Anthony Danza (born 1971) and Gina Danza (born 1983). Gina was born during a reconciliation. Tony and Rhonda later separated again.
- Attended and graduated from Malverne Senior High School in Malverne, Nassau County, New York (1968).
- Turned down the role of Swan in The Warriors (1979) for the role of Tony Banta on Taxi (1978). The role instead went to Michael Beck.
- Almost always watches the television series 24h Chống Khủng Bố (2001) with Liza Minnelli.
- As of 2018, has appeared in one Academy Award nominee/winner for Best Picture: Đổ Vỡ (2004).
- Was named as "King of Brooklyn" at the Welcome Back to Brooklyn Festival (1999).
- As a professional boxer, he fought in Brooklyn, New York City, Long Island, Nanuet, White Plains, and Phoenix.
- On May 9, 2005, he escaped a serious injury when the mini stock-car he was driving flipped over and he wasn't wearing a helmet.
- Danza scored first-round knockouts over Earl Harris, Joe Marcetti, Ralph Garcia, Ray Bryant, Tony Rodriguez, Billy Perez, and Max Hord.
- The metal rock band The Tony Danza Tap Dance Extravaganza was named after the actor.
- He was awarded a Star on the Hollywood Walk of Fame for Television at 7000 Hollywood Boulevard in Hollywood, California on November 21, 1988.
- He lost three fights as a professional boxer: a first-round knockout to John LoCicero on October 1, 1976, a four-round decision to Barry Hill on April 21, 1977, and a first-round knockout loss to Morris Watkins on November 11, 1977.
- Has an Italian-Canadian cousin named Daniel Gianotti.
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