Medical research articles from across Nature Portfolio

Extreme weather events are increasingly linked to violence. A new study finds that exposure to floods increases risk of intimate-partner violence among women, especially among more vulnerable populations.

The long-term safety of genetically modified T cells for therapeutic applications remains a crucial concern. A comprehensive analysis of 783 patients across multiple clinical trials, with >2,200 patient-years of follow-up, found no strong evidence linking these therapies to insertional oncogenesis.

l-Asparaginase (L-ASP) is a standard therapy for leukemias but not solid tumours. In a compassionate-use trial for nasopharyngeal carcinoma, Chang et al. report that L-ASP enhances the anti-tumour T cell response with clinical benefits when combined with pembrolizumab. This study provides proof of concept for ‘metabolic-immunotherapy’ in cancer.

The popular repositories, where life scientists post research before peer review, will be managed by a new organization called openRxiv.

Measurements of neurofilament light chain, glial fibrillary acidic protein and contactin 1 in plasma can provide useful prognostic information following traumatic spinal cord injury, according to new research.