Carlo Pedretti was born on 6 January 1928 in Casalecchio di Reno, Emilia-Romagna, Italy. He was married to Rossana. He died on 5 January 2018 in Lamporecchio, Pistoia, Tuscany, Italy.
Leading authority on Leonardo Da Vinci and Emeritus professor of Art History and Armand Hammer Chair in Leonardo Studies at UCLA, he was the author of numerous books.