- Played a regular or recurring character named "Arnold Spivak" in two different television series nearly two decades apart: lawyer Arnold Spivak in ABC prime time series Murder One (1995), and Dr. Arnold Spivak in the original Netflix horror series Thị Trấn Hemlock Grove (2013).
- He played a character named "Dr. Fred Spivak" as a recurring guest on the series, The Practice (1997), and a character named "Arnold Spivak" as a series regular on Murder One (1995).
- Has worked with Scorsese five times - The Aviator (2004), The Departed (2006), The Wolf of Wall Street (2013), Vinyl (2016) for HBO and The Irishmen (2019).
- In the play Toad of Toad Hall there were two different "pantomime" horses. Two different actors played the fronts of the two different horses, but MacKenzie played the backside of both.
- Has a son, Liam, with Erin Cressida Wilson.
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