- At 6'8, he is the tallest actor to play Michael Myers.
- Was a professional wrestler.
- To prepare for his role as Michael Myers he watched all of the Halloween films, except for Halloween 3.
- Watched the 1990's X-Men cartoon and looked back at Sabertooth for inspiration. Purchased dozens of Sabertooth Comics to prepare for his role in the movie X-Men.
- While wrestling in WCW as Big Sky in the early-1990s, he teamed regularly with Vinnie Vegas (Kevin Nash) right before Nash's WWF tenure as "Diesel".
- Trained for his audition for a role in the movie re-make "Rollerball (2002)" (which also starred fellow X-Men alumnus Rebecca Romijn) in the San Fernando Valley roller rink Moonlight Rollerway for a week, but did not succeed in landing a role.
- Ironically given his name, in the film that made him famous, X-Men (2000), Tyler Mane plays Sabretooth, a half-man, half-feline mutant with a full head of hair. Mane reprises the role of Sabretooth in "Deadpool & Wolverine" (2024).
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