- A Las Vegas cabbie enlists the help of a U.F.O. expert to protect two siblings with paranormal powers from the clutches of an organization that wants to use the kids for their nefarious plans.
- In Las Vegas, regenerated ex-con Jack Bruno works as a taxi driver. During a UFO Convention at Planet Hollywood, the skeptical Jack picks up Dr. Alex Friedman, who will present a scientific lecture at the event. Then he is pressed by two henchmen of his former boss, the criminal Wolff, who wants to talk to him, but Jack does not want to return to the crime life. Jack fights and gets rid of them; out of the blue, he finds two teenagers on the backseat of his cab. They say they are siblings, Sara and Seth, and they need to travel to a location outside Las Vegas in the middle of nowhere. Meanwhile, the government finds a spacecraft that crashed near Las Vegas and chases the two aliens; after the investigation of the men of Major Henry Burke, they discover that the two siblings are the aliens. Jack Bruno, Sara and Seth are chased by Henry Burke's team and by "Syphon", a killer from outer space sent to kill them by their planet's military that wants to invade Earth. Sara and Seth explain that they traveled to Earth to collect scientific data of an experiment and save Earth from invasion, but they need to return immediately to their planet. Jack teams up with Dr. Alex to retrieve their spacecraft in a secret base in Witch Mountain.—Claudio Carvalho, Rio de Janeiro, Brazil
- After crash-landing their fast spaceship on the Earth, somewhere in the hot deserts of Searchlight, Nevada, the teen, human-like extraterrestrial siblings, Sara and Seth, end up in the back seat of the former mob getaway driver and now a Las Vegas cabbie, Jack Bruno. Now, with their lives, and the fate of their world, lying in Jack's hands, the twins embark on a frenzied adventure in the wilderness, as the U.S. Homeland Security agents and an armed-to-the-teeth alien bounty hunter are hot on their trail. Now, the race is on, and the unlikely team's only chance to succeed in their dangerous mission lies deep in the heart of the mystical Witch Mountain. Can they make it in time?—Nick Riganas
- A middle-aged male taxi driver and a middle-aged female scientist must work together to help two teenage alien siblings who are trying to get back home. However, a sinister government agency is hunting down the alien siblings so they can test experiments on them.—RECB3
- During the opening credits, news of UFO sightings around the world appear.
Jack Bruno (Dwayne Johnson) is a cab driver in Las Vegas, who is picking up and dropping off passengers to the UFO convention at the Planet Hollywood Casino and Hotel. One of his passengers is Dr. Alex Friedman (Carla Gugino), a failed scientist who is giving speeches about legitimate scientific theories of UFOs and outer space.
The next day Bruno is approached by two large men telling him that Wolff would like to see him. After fighting them, Bruno drives off, later noticing two children, Sara (AnnaSophia Robb) and Seth (Alexander Ludwig) sitting in the back seat of the cab. They tell him they need to go to a certain destination and are willing to pay all they have ($15,000) to get there. Along the way, there are chased & vehicularly assaulted by guys in big black SUV's, whom Jack assumes are Wolff's men...not so, grasshopper. With a combination of Jack's driving & (mostly) the kids' powers, they evade their pursuers, who intend to find out who & what Jack is. They lead him to a run down house in the middle of nowhere. Meanwhile, Major Henry Burke (Ciaran Hinds) is searching for information on the two aliens that landed some days earlier.
When they arrive at the house, the children tell Bruno that they will be re-united with their relatives soon. Before leaving Bruno hears a crash coming from the house. He is startled to find them hiding behind a couch. Though grateful for his concern, the children tell him they must continue their journey without him, as they can trust no one. Nevertheless, Bruno decides to follow them, which leads him to the basement of the house. There the kids are pursued and attacked by a strange creature as they retrieve an object in a plant. They manage to escape from this creature.
When leaving they are attacked by a "Siphon", a creature built to destroy a certain target, in this case the children. The Siphon pursues them until it causes a crash of his spaceship into a train, the creature survives, though wounded. The trio eventually find themselves in a small town, hiding. They explain to Bruno that they are aliens from an distant planet, who are sent to Earth by their parents because the government of their dying planet intends to attack and invade Earth so that their kind may live on there. They also explain that the object they obtained at the house contains the results of an experiment which their parents set up. The research from this experiment will save their planet without having to attack and invade Earth. However their planet's military prefer the idea of invading Earth and sent the Siphon assassin to stop them. They are next pursued by government agencies trying to retrieve the children for experiments.
When Sara asks who Dr. Friedman is (did i mention the kids' mind-reading capabilities?), Jack remembers she is a scientist speaking at the UFO convention. They find her, tell her the whole story & convince her to help them. She does this by enlisting the aid of Dr. Harlan (Garry Marshall), a pseudo-scientist/conspiracy nut. All proceed to the UFO convention.
When the Siphon arrives, it prepares to attack but Sara uses her powers to knock him through a wall. Chases ensue, & eventually the team of 4 are captured by Maj. Burke. Burke wants to terminate Sara & Seth, but one of his underlings objects, tho not strenuously enough to disobey orders. The two humans escape and come to rescue the kids. The Siphon causes a distraction by attacking the base. They manage to free the children and reach their ship. By running the Siphon over they can escape but the Siphon hangs on and gets on board. Bruno and Seth battle the Siphon in the lower sections of the ship, unmasking him in the fight. Finally, Bruno defeats the evil alien by knocking him out of the ship's airlock, which kills him. Nothing is mentioned about the fate of Henry Burke, though he was last seen disappointed and upset for his failure and was talking to his boss on the phone, with a possibly of getting fired. The kids drop Jack and Alex off and after a tearful goodbye, they head back to their ship, but give Bruno and Alex a device that will allow the kids to always find them. And Sara gives Jack the power to use his brain to the mind reading ability.
During the end credits, Bruno and Dr. Friedman (now a couple) are speaking at a UFO convention about their new successful book called "Race to Witch Mountain". The last scene shows them driving off in a car Bruno dreamed of getting honestly as he had mentioned to Friedman earliera Ford Mustang similar to that driven by Steve McQueen in ''Bullitt''. As they are about to leave, the device the kids gave Bruno before they left goes off, indicating that they may be returning. [D-Man2010]
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