Lou Costello, in his youth a basketball player who specialized in dead-eye free-throw shooting, pumped in many of the shots himself during the film's basketball game.
Just before his comic song-and-dance with Peggy Ryan, Lou Costello jokes, "I feel just like Donald O'Connor!" This is an in-joke reference to the series of films Universal was then making with O'Connor and Ryan as co-stars, copying the formula of the Mickey Rooney-Judy Garland films at MGM.
This was the first of only two Bud Abbott and Lou Costello films produced by their longtime writer John Grant.
Lon Chaney Jr. would appear in "Abbott and Costello Meet Frankenstein" in 1948.
The first time the oyster soup sketch was filmed was in the 1926 Billy Bevan film, Wandering Willies, directed by Del Lord who also directed it again in the 1941 Three Stooges film, Dutiful But Dumb. Later it is seen in the 1945 Abbott and Costello film, Here Come the Co-eds, and also their 1953 TV show. Larry Fine also did a similar skit with a bowl of gumbo and a lobster in the 1955 Three Stooges film, Income Tax Sappy.