Ergosterol
Ergosterol (ergosta-5,7,22-trien-3β-ol) je sterol prisutan u gljivicama, i imenovan po ergotu, zajedničkom imenu za članove gljivičnog roda Claviceps iz koga su ergosteroli prvobitno izolovani. Ergosterol se ne javlja u biljnim i životinjskim ćelijama. On je komponenta ćelijske membrane kvasca i gljivica, gde ima istu ulogu kao i holesterol u životinjskim ćelijama.
Ergosterol | |||
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IUPAC ime |
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Identifikacija | |||
CAS registarski broj | 57-87-4 | ||
PubChem[1][2] | 444679 | ||
ChemSpider[3] | 392539 | ||
UNII | Z30RAY509F | ||
EINECS broj | |||
MeSH | |||
ChEBI | 16933 | ||
ChEMBL[4] | CHEMBL1232562 | ||
Jmol-3D slike | Slika 1 | ||
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Svojstva | |||
Molekulska formula | C28H44O | ||
Molarna masa | 396,65 g/mol | ||
Tačka topljenja |
160.0 °C | ||
Tačka ključanja |
250.0 °C | ||
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala | |||
Infobox references |
Ergosterol se javlja u travama poput raži[5] i lucerke, kao i u cvetajućim biljkama, npr. hmelju.[6]. Međutim, obično se smatra da je ergosterol detektovan zbog fungalnog rasta na biljkama (kontaminacije), jer glijvice formiraju intergralni deo sistema razlaganja trave. Ergosterolni testovi se mogu koristiti za određivanje fungalnog sadržaja u travi, žitaricama i storčnoj hrani.[7][8].
Reference
uredi- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.
- ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.
- ↑ Tartaglia LA, Storz G, Brodsky MH, Lai A, Ames BN. (1990-06-25). „Alkyl hydroperoxide reductase from Salmonella typhimurium. Sequence and homology to thioredoxin reductase and other flavoprotein disulfide oxidoreductases”. J Biol Chem. 265: 10535-40.
- ↑ Magalhães PJ, Carvalho DO, Guido LF, Barros AA. (2007-09-03). „Detection and quantification of provitamin D2 and vitamin D2 in hop (Humulus lupulus L.) by liquid chromatography-diode array detection-electrospray ionization tandem mass spectrometry”. J Agric Food Chem 55: 7995-8002.
- ↑ Steven Y. Newell (2001). „Multiyear patterns of fungal biomass dynamics and productivity within naturally decaying smooth cordgrass shoots”. Limnol. Oceanogr. 46: 573–583.[mrtav link]
- ↑ Müller HM, Schwadorf K. (1990). „Ergosterol as a measure for fungal growth in feed. 2. Ergosterol content of mixed feed components and mixed feed”. Arch Tierernahr 40: 385-95.
Spoljašnje veze
uredi- Safety (MSDS) data for ergosterol Arhivirano 2007-10-11 na Wayback Machine-u Oxford University (2005)