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NEK9

From Wikipedia, the free encyclopedia

NEK9
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesNEK9, NERCC, NERCC1, Nek8, NIMA related kinase 9, APUG, LCCS10, NC
External IDsOMIM: 609798; MGI: 2387995; HomoloGene: 13222; GeneCards: NEK9; OMA:NEK9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_033116
NM_001329237
NM_001329238

NM_145138

RefSeq (protein)

NP_001316166
NP_001316167
NP_149107

NP_660120

Location (UCSC)Chr 14: 75.08 – 75.13 MbChr 12: 85.35 – 85.39 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Serine/threonine-protein kinase Nek9 is an enzyme that in humans is encoded by the NEK9 gene.[5][6]

Interactions

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NEK9 has been shown to interact with:

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000119638Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034290Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Holland PM, Milne A, Garka K, Johnson RS, Willis C, Sims JE, Rauch CT, Bird TA, Virca GD (May 2002). "Purification, cloning, and characterization of Nek8, a novel NIMA-related kinase, and its candidate substrate Bicd2". The Journal of Biological Chemistry. 277 (18): 16229–40. doi:10.1074/jbc.M108662200. PMID 11864968.
  6. ^ "Entrez Gene: NEK9 NIMA (never in mitosis gene a)- related kinase 9".
  7. ^ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3: 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
  8. ^ Belham C, Roig J, Caldwell JA, Aoyama Y, Kemp BE, Comb M, Avruch J (Sep 2003). "A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases". The Journal of Biological Chemistry. 278 (37): 34897–909. doi:10.1074/jbc.M303663200. PMID 12840024.
  9. ^ a b Roig J, Mikhailov A, Belham C, Avruch J (Jul 2002). "Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression". Genes & Development. 16 (13): 1640–58. doi:10.1101/gad.972202. PMC 186374. PMID 12101123.
  10. ^ Tan BC, Lee SC (Mar 2004). "Nek9, a novel FACT-associated protein, modulates interphase progression". The Journal of Biological Chemistry. 279 (10): 9321–30. doi:10.1074/jbc.M311477200. PMID 14660563.

Further reading

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