(Q52102307)

22 April 2018

title

Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42. (English)

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22 April 2018

author name string

Zhong Li

1

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22 April 2018

Michael Hannigan

2

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22 April 2018

Zhicheng Mo

3

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22 April 2018

Bo Liu

4

1 reference

22 April 2018

Wei Lu

5

1 reference

22 April 2018

Yue Wu

6

1 reference

22 April 2018

Alan V Smrcka

7

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22 April 2018

Guanqing Wu

8

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22 April 2018

Lin Li

9

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22 April 2018

Mingyao Liu

10

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22 April 2018

Chi-Kuang Huang

11

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22 April 2018

Dianqing Wu

12

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22 April 2018

language of work or name

English

0 references

publication date

1 July 2003

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22 April 2018

published in

Cell

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22 April 2018

volume

114

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22 April 2018

issue

2

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22 April 2018

page(s)

215-227

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22 April 2018

A role for Cdc42 in macrophage chemotaxis

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

1 reference

7 January 2021

Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Regulation of cell function by Rho family GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

1 reference

7 January 2021

The role of Far1p in linking the heterotrimeric G protein to polarity establishment proteins during yeast mating

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Signaling pathways controlling cell polarity and chemotaxis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

p21-activated protein kinase: a crucial component of morphological signaling?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

alphaPix stimulates p21-activated kinase activity through exchange factor-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Localization of p21-activated kinase 1 (PAK1) to pseudopodia, membrane ruffles, and phagocytic cups in activated human neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Multiple roles for Cdc42 in cell regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Rho GTPases in cell biology

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Regulation of the Cool/Pix proteins: key binding partners of the Cdc42/Rac targets, the p21-activated kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Pak functions downstream of Dock to regulate photoreceptor axon guidance in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Stimulation of a Histone H4 Protein Kinase in Triton X-100 Lysates of Rabbit Peritoneal Neutrophils Pretreated With Chemotactic Factors: Effect of Leukotriene B4 and Cytochalasin B

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Neutrophils stimulated with a variety of chemoattractants exhibit rapid activation of p21-activated kinases (Paks): separate signals are required for activation and inactivation of paks

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Tumor suppressor PTEN mediates sensing of chemoattractant gradients.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Temporal and spatial regulation of chemotaxis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

A role for p21-activated kinase in endothelial cell migration.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Mutations in ARHGEF6, encoding a guanine nucleotide exchange factor for Rho GTPases, in patients with X-linked mental retardation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Interaction of a G-protein beta-subunit with a conserved sequence in Ste20/PAK family protein kinases.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Mechanism of activation of Pak1 kinase by membrane localization

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

The molecular biology of leukocyte chemoattractant receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

A cell's sense of direction

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

The Cdc42/Rac interactive binding region motif of the Wiskott Aldrich syndrome protein (WASP) is necessary but not sufficient for tight binding to Cdc42 and structure formation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Signaling to the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Reciprocal Signaling between Heterotrimeric G Proteins and the p21-stimulated Protein Kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Genomic structure of human alpha-pix, and variable deletions in a poly (T) tract in gastric cancer tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

Orientation chamber in chemotaxis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2900559-2

7 January 2021

10.1016/S0092-8674(03)00559-2

Identifiers

DOI

1 reference

22 April 2018

1 reference

22 April 2018